As we wander through the historic Senado Square in Macau, the imposing façade of the Holy House of Mercy, or Santa Casa da Misericórdia, beckons us to explore its rich history. This 16th-century institution was more than just a charity; it was the backbone of Macau's early social welfare system, providing aid to the poor, the sick, and the marginalized. Within its walls lies a museum that houses a fascinating relic - the skull of Bishop Belchior Carneiro, Macau's first bishop. The Holy House of Mercy was founded by the Portuguese nobility in the early days of Macau's colonization. It was an era when the city was still a fledgling trading post, struggling to establish itself amidst the vast and complex networks of Asian commerce. The 'Brotherhood of Our Lady of Mercy,' a confraternity associated with the Holy House, played a pivotal role in managing social welfare in a city divided by language, culture, and class. They provided shelter, food, and medical care to those in need, regardless of their background. As we step into the museum, we are greeted by a collection of artifacts that tell the story of Macau's early days. Among these is the skull of Bishop Belchior Carneiro, a Jesuit who arrived in Macau in 1568. He was instrumental in establishing the city's first Catholic diocese and played a significant role in the Jesuit mission in Asia. The skull, now a revered relic, is a poignant reminder of the sacrifices made by early missionaries who brought Christianity to the region. The museum also showcases the history of the Holy House of Mercy, highlighting its charitable works and the impact it had on the community. Through its various exhibitions, we gain insight into the lives of the people who lived in Macau during the 16th and 17th centuries, and how the Brotherhood of Our Lady of Mercy worked tirelessly to provide for those in need. As we explore the museum, we are struck by the rich cultural heritage that Macau has inherited from its complex history. The Holy House of Mercy is a testament to the city's unique blend of Portuguese and Asian influences, and the skull of Bishop Belchior Carneiro is a powerful symbol of the faith and resilience that defined the early days of Macau's colonization.